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Sarcomatoid Renal Cell Carcinoma

Names  l  Define  l  Risk  l  Detect  l  Treatment  l  Stage/Grade  l  Followup  l  Mets/Recur  l  Link

Names - Synonyms

Sarcomatoid Renal Cell Carcinoma is not an entity by itself.  It is a rare progression of Renal Cell Carcinoma; therefore it may also be referred to as renal cell carcinoma - sarcomatoid variant, differentiation, or transformation.

Definition

The sarcomatoid progression of Renal Cell Carcinoma  is characterized as highly proliferative, with a lower response to treatment;  higher metastatic and local recurrence rate; and shorter survival time.

Sarcomatoid dedifferentiation may arise from any of the recognized types of renal cell carcinoma.  Sarcomatoid renal cell carcinoma is not a diagnostic category independent of the others.  

Risk Factors - Causes

Refer to Renal Cell Carcinoma

Detection

Refer to Renal Cell Carcinoma

Treatment

Refer to Renal Cell Carcinoma

Stage - Grade

TNM stage appeared to be the only significant variable in predicting outcome among renal cell carcinomas with sarcomatoid change.  

Renal cell carcinoma (RCC) tumors with sarcomatoid change tend to be diagnosed at a more advanced stage.

Suggested Followups

Refer to Renal Cell Carcinoma

Metastasis - Recurrence

Refer to Renal Cell Carcinoma

Link

Sarcomatoid Renal Cell Carcinoma Support Forums