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Trial - CNS Tumor (100 unread)

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Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer

Posted: May 23rd, 2012, 8:00am MDT

Conditions: Advanced Colorectal Adenomas; Adenocarcinoma of the Colon; Stage I Colon Cancer; Stage II Colon Cancer; Stage III Colon Cancer
Interventions: Drug: defined green tea catechin extract; Other: placebo; Other: questionnaire administration; Other: laboratory biomarker analysis
Sponsors: Mayo Clinic; Mayo Clinic; National Cancer Institute (NCI)
Not yet recruiting - verified May 2012
Hypernatremia for the Prevention and Treatment of Cerebral Edema in Traumatic Brain Injury

Posted: May 22nd, 2012, 8:00am MDT

Conditions: Traumatic Brain Injury; Subdural Hematoma; Cerebral Contusion; Head Injury; Cerebral Edema
Interventions: Drug: Induced, sustained hypernatremia using hypertonic saline; Drug: Standard of care (hypertonic saline and mannitol; serum sodium)
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Not yet recruiting - verified May 2012
A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression

Posted: May 21st, 2012, 8:00am MDT

Condition: Brain Cancer
Intervention: Other: MRI perfusion and PET/CT scans
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center
Recruiting - verified May 2012
Procedural Pain Treatment With Transmucosal Sublingual Fentanyl Tablet in Colonoscopy Patients

Posted: May 21st, 2012, 8:00am MDT

Conditions: Colonoscopy; Pain
Interventions: Drug: Fentanyl; Drug: Placebo
Sponsors: Turku University Hospital; Turku University Hospital
Recruiting - verified May 2012
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

Posted: May 18th, 2012, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: carboplatin; Drug: etoposide; Drug: ifosfamide; Procedure: therapeutic conventional surgery; Radiation: 3-dimensional conformal radiation therapy; Radiation: intensity-modulated radiation therapy
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Not yet recruiting - verified May 2012
Systemic Therapy With Interferon, Interleukin-2 and BRAF Inhibitor

Posted: May 18th, 2012, 8:00am MDT

Condition: Melanoma
Interventions: Drug: Vemurafenib; Drug: IL-2; Drug: Interferon Alpha-2b
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Not yet recruiting - verified May 2012
A Study of Tabalumab in Participants With Previously Treated Multiple Myeloma (MM)

Posted: May 16th, 2012, 8:00am MDT

Condition: Multiple Myeloma
Interventions: Drug: Placebo; Drug: Dexamethasone; Drug: Bortezomib; Biological: Tabalumab
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Not yet recruiting - verified May 2012
Social Cognition in Children Treated for a Brain Tumour

Posted: May 11th, 2012, 8:00am MDT

Conditions: Social Behaviour; Brain Neoplasms; Cystic Fibrosis
Intervention:
Sponsors: University Medical Centre Groningen; University Medical Centre Groningen; Radboud University; Universitaire Ziekenhuizen Leuven
Recruiting - verified May 2012
Duloxetine Hydrochloride in Treating Muscle, Bone, and Joint Pain in Patients With Early-Stage Breast Cancer Receiving Hormone Therapy

Posted: May 11th, 2012, 8:00am MDT

Conditions: Breast Cancer; Musculoskeletal Complications; Pain; Therapy-related Toxicity
Interventions: Drug: duloxetine hydrochloride; Other: placebo
Sponsors: National Cancer Institute (NCI); Southwest Oncology Group; National Cancer Institute (NCI)
Not yet recruiting - verified May 2012
Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients

Posted: May 10th, 2012, 8:00am MDT

Conditions: Seizures (Incl Subtypes); Brain Tumor
Interventions: Drug: Magnesium Sulfate; Other: Sodium Chloride
Sponsors: Fundacion Clinic per a la Recerca Biomédica; Sara Varea
Not yet recruiting - verified May 2012
Safety and Efficacy of Cannabidiol for Grade I/II Acute Graft Versus Host Disease (GVHD) After Allogeneic Stem Cell Transplantation

Posted: May 9th, 2012, 8:00am MDT

Condition: Graft Versus Host Disease
Intervention: Drug: Cannabidiol
Sponsors: Rabin Medical Center; Rabin Medical Center
Not yet recruiting - verified May 2012
Longitudinal Study of Biomarkers

Posted: May 8th, 2012, 8:00am MDT

Condition: Central Nervous System Tumor
Intervention:
Sponsors: Children's Memorial Hospital; Children's Memorial Hospital
Recruiting - verified May 2012
MicroRNAs in Patients With Neurofibromatosis Type 1

Posted: May 8th, 2012, 8:00am MDT

Conditions: Glioma; Neurofibromatosis Type 1
Intervention:
Sponsors: Children's Memorial Hospital; Children's Memorial Hospital
Recruiting - verified May 2012
Combination Chemotherapy With or Without Rituximab in Treating Younger Patients With Stage III-IV Non-Hodgkin Lymphoma or B-Cell Acute Leukemia

Posted: May 8th, 2012, 8:00am MDT

Conditions: Leukemia; Lymphoma
Interventions: Biological: rituximab; Drug: cyclophosphamide; Drug: cytarabine; Drug: doxorubicin hydrochloride; Drug: etoposide; Drug: hydrocortisone sodium succinate; Drug: leucovorin calcium; Drug: methotrexate; Drug: methylprednisolone; Drug: prednisone; Drug: vincristine sulfate
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Not yet recruiting - verified May 2012
Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System

Posted: May 8th, 2012, 8:00am MDT

Conditions: Leukemia; Lymphoid Malignancies; Metastatic Malignant Neoplasm to the Leptomeninges
Intervention: Drug: Intrathecal Rituximab
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Not yet recruiting - verified May 2012
Phase I Study of Cabazitaxel, Mitoxantrone, and Prednisone (CAMP) for Patients With Metastatic Castration-Resistant Prostate Cancer and no Prior Chemotherapy

Posted: May 7th, 2012, 8:00am MDT

Condition: Metastatic Castration-resistant Prostate Cancer
Interventions: Drug: Cabazitaxel; Drug: Mitoxantrone; Drug: Prednisone; Drug: Pegfilgrastim
Sponsors: University of California, San Francisco; Andrea Harzstark; Sanofi-Aventis
Not yet recruiting - verified May 2012
Mirtazapine Plus Gemcitabine Versus Gemcitabine in Metastasis Pancreatic Cancer

Posted: May 5th, 2012, 8:00am MDT

Condition: Pancreatic Cancer
Interventions: Drug: Mirtazapine plus gemcitabine; Drug: Gemcitabine, placebo
Sponsors: Tianjin Medical University Cancer Institute and Hospital; Tianjin Medical University Cancer Institute and Hospital
Not yet recruiting - verified May 2012
Decitabine and Vorinostat With CD3/CD19 Depleted Haploidentical Donor NK Cells for Treatment of High Risk Myelodysplastic Syndromes

Posted: May 4th, 2012, 8:00am MDT

Condition: Myelodysplastic Syndrome
Interventions: Drug: Decitabine; Drug: Vorinostat; Biological: Interleukin-2; Other: Natural killer (NK) cells
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Not yet recruiting - verified May 2012
A Prospective Phase III Trial to Compare Stereotactic Radiosurgery Versus Whole Brain Radiation Therapy

Posted: May 3rd, 2012, 8:00am MDT

Condition: Brain Neoplasms
Interventions: Radiation: Stereotactic Radiosurgery (SRS); Radiation: Whole Brain Radiation Therapy (WBRT); Behavioral: Questionnaires; Behavioral: Cognitive Function Tests
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Not yet recruiting - verified May 2012
Aerosol IL-2 for Pulmonary Metastases

Posted: April 30th, 2012, 8:00am MDT

Conditions: Sarcoma; Solid Tumors; Pulmonary Metastases; Lung Metastases; Osteosarcomas; Ewing Sarcoma
Interventions: Drug: Aerosol IL-2; Procedure: Symptom Assessment
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Shannon Wilkes Foundation
Not yet recruiting - verified May 2012
Structural and Functional Imaging and Cognitive Functions in Ovarian Cancer

Posted: April 30th, 2012, 8:00am MDT

Conditions: Fallopian Tube Cancer; Ovarian Cancer; Peritoneal Cancer
Interventions: Other: Neuroimaging & Neuropsychological Evaluation; Other: Neuroimaging & Neuropsychological Evaluation
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Weill Medical College of Cornell University
Recruiting - verified May 2012
ch14.18 Pharmacokinetic Study in High-risk Neuroblastoma

Posted: April 30th, 2012, 8:00am MDT

Condition: Neuroblastoma
Interventions: Biological: ch14.18 -NCI; Biological: ch14.18-UTC; Biological: Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF); Biological: Aldesleukin (IL-2); Drug: Isotretinoin
Sponsors: United Therapeutics; United Therapeutics
Not yet recruiting - verified May 2012
$Permalink for 'Pomalidomide (POM) in Combination With Low Dose Dexamethasone (LD-Dex) in Patients With Relapsed or Refractory Multiple Myeloma'$
Pomalidomide (POM) in Combination With Low Dose Dexamethasone (LD-Dex) in Patients With Relapsed or Refractory Multiple Myeloma

Posted: April 27th, 2012, 8:00am MDT

Condition: Multiple Myeloma
Intervention: Drug: Pomalidomide
Sponsors: Celgene Corporation; Celgene Corporation
Available - verified May 2012
The Value of Botox-A for Management of Low Anterior Resection Syndrome

Posted: April 27th, 2012, 8:00am MDT

Conditions: Low Anterior Resection Syndrome; Rectal Cancer
Intervention: Drug: intra-rectal Botulinum toxin A injection
Sponsors: Centre hospitalier de l'Université de Montréal (CHUM); Centre hospitalier de l'Université de Montréal (CHUM); Allergan
Recruiting - verified June 2011
Liposomal Cytarabine in the Treatment of Central Nervous System Resistant or Relapsed Acute Lymphoblastic Leukemia in Children

Posted: April 27th, 2012, 8:00am MDT

Condition: Acute Lymphoblastic Leukemia
Intervention: Drug: liposomal cytarabine
Sponsors: National Cancer Institute, Naples; National Cancer Institute, Naples; Santobono-Pausilpon Hospital; Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi; University of Bologna
Recruiting - verified May 2012
Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Posted: April 26th, 2012, 8:00am MDT

Conditions: Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Promyelocytic Leukemia (M3); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma; Anaplastic Large Cell Lymphoma; B-cell Adult Acute Lymphoblastic Leukemia; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cytomegalovirus Infection; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Isolated Plasmacytoma of Bone; Monoclonal Gammopathy of Undetermined Significance; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Peripheral T-cell Lymphoma; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Central Nervous System Hodgkin Lymphoma; Primary Central Nervous System Non-Hodgkin Lymphoma; Primary Myelofibrosis; Progressive Hairy Cell Leukemia, Initial Treatment; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Multiple Myeloma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Multiple Myeloma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Large Granular Lymphocyte Leukemia; Untreated Adult Acute Myeloid Leukemia; Untreated Hairy Cell Leukemia; Waldenström Macroglobulinemia
Interventions: Biological: tetanus-CMV fusion peptide vaccine; Other: laboratory biomarker analysis
Sponsors: City of Hope Medical Center; City of Hope Medical Center; National Cancer Institute (NCI)
Not yet recruiting - verified April 2012
Three Anthracyclines, Two Types of Consolidation With Different ARA-C Doses and Maintenance in Adult AML

Posted: April 26th, 2012, 8:00am MDT

Condition: Acute Myeloid Leukemia
Intervention: Drug: daunorubicine, idarubicine, mitoxantrone
Sponsors: National Research Center for Hematology, Russia; National Research Center for Hematology, Russia
Recruiting - verified April 2012
Human Placental-Derived Stem Cell Transplantation

Posted: April 25th, 2012, 8:00am MDT

Conditions: Mucopolysaccharidosis I; Mucopolysaccharidosis VI; Adrenoleukodystrophy; Niemann-Pick Disease; Metachromatic Leukodystrophy; Wolman Disease; Krabbe's Disease; Gaucher's Disease; Fucosidosis; Batten Disease; Severe Aplastic Anemia; Diamond-Blackfan Anemia; Amegakaryocytic Thrombocytopenia; Myelodysplastic Syndrome; Acute Myelogenous Leukemia; Acute Lymphocytic Leukemia
Intervention: Drug: Human Placental Derived Stem Cell
Sponsors: New York Medical College; New York Medical College
Not yet recruiting - verified April 2012
Stress Management Training for Latinas Receiving Chemotherapy

Posted: April 23rd, 2012, 8:00am MDT

Conditions: Cancer; Stress
Interventions: Behavioral: Spanish-Language Self-Administered Training Plus Usual Care (SL-SAT); Behavioral: Usual Care Only
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute; American Cancer Society; University of Miami
Recruiting - verified May 2012
Vorinostat and Concurrent Whole Brain Radiotherapy for Brain Metastasis

Posted: April 23rd, 2012, 8:00am MDT

Condition: Brain Metastasis
Interventions: Drug: Vorinostat; Drug: Placebo
Sponsors: National Taiwan University Hospital; National Taiwan University Hospital
Not yet recruiting - verified April 2012
Safety Study of Replication-competent Adenovirus (Delta-24-rgd) in Patients With Recurrent Glioblastoma

Posted: April 19th, 2012, 8:00am MDT

Conditions: Brain Tumor; Recurring Glioblastoma
Intervention: Biological: delta-24-RGD adenovirus
Sponsors: Erasmus Medical Center; Erasmus Medical Center; VU University Medical Center
Recruiting - verified April 2012
Efficacy and Safety Evaluation of Carbamazepine for Prevention of Chemotherapy-induced Nausea and Vomiting.

Posted: April 19th, 2012, 8:00am MDT

Condition: Chemotherapy-induced Nausea and Vomiting
Intervention: Drug: Carbamazepine
Sponsors: Faculdade de Medicina do ABC; Faculdade de Medicina do ABC
Recruiting - verified April 2012
Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

Posted: April 18th, 2012, 8:00am MDT

Conditions: Brain Neoplasms; Central Nervous System Neoplasms
Interventions: Drug: TPI287; Drug: Bevacizumab
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Archer Biosciences, Inc.
Not yet recruiting - verified April 2012
Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Patients With Brain Tumors

Posted: April 17th, 2012, 8:00am MDT

Conditions: Adult Anaplastic Astrocytoma; Adult Anaplastic Ependymoma; Adult Anaplastic Meningioma; Adult Anaplastic Oligodendroglioma; Adult Brain Stem Glioma; Adult Choroid Plexus Tumor; Adult Craniopharyngioma; Adult Diffuse Astrocytoma; Adult Ependymoblastoma; Adult Ependymoma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Grade I Meningioma; Adult Grade II Meningioma; Adult Medulloblastoma; Adult Meningeal Hemangiopericytoma; Adult Mixed Glioma; Adult Myxopapillary Ependymoma; Adult Oligodendroglioma; Adult Papillary Meningioma; Adult Pilocytic Astrocytoma; Adult Pineal Gland Astrocytoma; Adult Pineoblastoma; Adult Pineocytoma; Adult Subependymal Giant Cell Astrocytoma; Adult Subependymoma; Adult Supratentorial Primitive Neuroectodermal Tumor (PNET); Meningeal Melanocytoma; Nonmalignant Neoplasm; Recurrent Adult Brain Tumor; Tumors Metastatic to Brain
Interventions: Drug: pioglitazone hydrochloride; Other: laboratory biomarker analysis; Radiation: external beam radiation therapy; Radiation: 3-dimensional conformal radiation therapy; Radiation: intensity-modulated radiation therapy; Procedure: management of therapy complications
Sponsors: Comprehensive Cancer Center of Wake Forest University; Comprehensive Cancer Center of Wake Forest University; National Cancer Institute (NCI)
Recruiting - verified April 2012
Prophylactic Cranial Irradiation in Patients With Lung Adenocarcinoma With High Risk of Brain Metastasis

Posted: April 17th, 2012, 8:00am MDT

Condition: Lung Cancer
Intervention: Radiation: Prophylactic Cranial Irradiation
Sponsors: Instituto Nacional de Cancerologia de Mexico; Instituto Nacional de Cancerologia de Mexico
Not yet recruiting - verified May 2012
Drug Interaction Study of SAR302503 in Patients With Solid Tumor

Posted: April 13th, 2012, 8:00am MDT

Condition: Solid Tumor
Interventions: Drug: SAR302503; Drug: omeprazol; Drug: metoprolol; Drug: midazolam
Sponsors: Sanofi-Aventis; Sanofi-Aventis
Not yet recruiting - verified April 2012
Botulinum Toxin A (Botox) in Tissue Expander Breast Reconstruction

Posted: April 13th, 2012, 8:00am MDT

Conditions: Breast Cancer; Pain, Postoperative; BRCA1 Mutation; BRCA2 Mutation; Breast Diseases; Neoplasms
Interventions: Drug: Botulinum Toxin Type A; Drug: Sodium Chloride Solution
Sponsors: Mayo Clinic; Mayo Clinic
Not yet recruiting - verified May 2012
An Open-label, Multi-center, Expanded Access Study of Pasireotide s.c. in Patients With Cushing's Disease

Posted: April 12th, 2012, 8:00am MDT

Condition: Cushing's Disease
Intervention: Drug: Pasireotide sub-cutaneous formulation
Sponsors: Novartis; Novartis Pharmaceuticals
Available - verified April 2012
A Pilot Study to Determine the Effect of Sulfasalazine on Glutamate Levels Detected by MRS in Patients With Glioma

Posted: April 11th, 2012, 8:00am MDT

Condition: Brain Tumor
Intervention: Drug: Sulfasalazine
Sponsors: University of Alabama at Birmingham; University of Alabama at Birmingham
Recruiting - verified April 2012
Erlotinib Plus Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases

Posted: April 11th, 2012, 8:00am MDT

Conditions: Lung Adenocarcinoma; Brain Metastases
Interventions: Drug: erlotinib; Drug: pemetrexed; Drug: cisplatin; Drug: erlotinib
Sponsors: Guangzhou Medical College; Guangzhou Medical College
Recruiting - verified April 2012
Study of ACY-1215 in Combination With Lenalidomide, and Dexamethasone in Multiple Myeloma

Posted: April 11th, 2012, 8:00am MDT

Condition: Multiple Myeloma
Interventions: Drug: ACY-1215; Drug: lenalidomide; Drug: Dexamethasone
Sponsors: Acetylon Pharmaceuticals Incorporated; Acetylon Pharmaceuticals Incorporated
Not yet recruiting - verified April 2012
Study of Pomalidomide to Evaluate the Pharmacokinetics and Safety for Patients With Multiple Myeloma and Impaired Renal Function

Posted: April 10th, 2012, 8:00am MDT

Condition: Multiple Myeloma
Interventions: Drug: Oral Pomalidomide (POM) and Oral Dexamethasone (LD-DEX) (Cohort A); Drug: Oral Pomalidomide (POM) and Oral Dexamethasone (LD-DEX) (Cohort B)
Sponsors: Celgene Corporation; Celgene Corporation
Not yet recruiting - verified April 2012
Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme

Posted: April 9th, 2012, 8:00am MDT

Conditions: Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Tumor
Interventions: Drug: aminolevulinic acid; Procedure: therapeutic conventional surgery
Sponsors: Case Comprehensive Cancer Center; Case Comprehensive Cancer Center; National Cancer Institute (NCI)
Not yet recruiting - verified April 2012
Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: A Clinical and Correlative Study

Posted: April 5th, 2012, 8:00am MDT

Condition: Multiple Myeloma
Interventions: Drug: Carfilzomib; Drug: Lenalidomide; Drug: Dexamethasone
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified March 2012
Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancer

Posted: April 3rd, 2012, 8:00am MDT

Condition: Small Cell Lung Cancer
Intervention: Drug: Chloroquine
Sponsors: Maastricht Radiation Oncology; Maastricht Radiation Oncology
Not yet recruiting - verified April 2012
Targeted BEACOPP Variants in Patients With Newly Diagnosed Advanced Classical Hodgkin Lymphoma

Posted: April 2nd, 2012, 8:00am MDT

Condition: Hodgkin Lymphoma
Interventions: Drug: Etoposide; Drug: Cyclophosphamide; Drug: Doxorubicin; Drug: Prednisone; Drug: Procarbazine; Drug: Dexamethasone; Drug: Dacarbazine; Drug: Brentuximab Vedotin
Sponsors: University of Cologne; University of Cologne
Not yet recruiting - verified March 2012
$Permalink for 'Investigation of Vorinostat in Combination With Intravenous Fludarabine, Mitoxantrone, and Dexamethasone in Patients With Relapsed or Refractory Mantle Cell Lymphoma'$
Investigation of Vorinostat in Combination With Intravenous Fludarabine, Mitoxantrone, and Dexamethasone in Patients With Relapsed or Refractory Mantle Cell Lymphoma

Posted: March 30th, 2012, 8:00am MDT

Condition: Mantle Cell Lymphoma
Intervention: Drug: Fludarabine, Mitoxantrone, Dexamethasone, Vorinostat
Sponsors: Samsung Medical Center; Samsung Medical Center
Not yet recruiting - verified April 2012
Calcium Homeostasis in Acromegaly: Effect of Surgical/Medical Treatment and Comparison With Nonfunctioning Pituitary Tumors

Posted: March 29th, 2012, 8:00am MDT

Conditions: Acromegaly; Nonfunctioning Pituitary Tumor
Intervention:
Sponsors: Emory University; Emory University
Recruiting - verified March 2012
Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas

Posted: March 29th, 2012, 8:00am MDT

Condition: Pediatric High Risk Gliomas
Intervention: Drug: Combination of two marketed drugs (irinotecan and cisplatin)
Sponsors: Hospital Sant Joan de Deu; Hospital Sant Joan de Deu; Fundació Sant Joan de Déu; Spanish National Health System
Recruiting - verified April 2012
Phase 3 Study With Carfilzomib and Dexamethasone Versus Velcade and Dexamethasone for Relapsed Multiple Myeloma Patients

Posted: March 28th, 2012, 8:00am MDT

Condition: Multiple Myeloma
Interventions: Drug: Carfilzomib plus dexamethasone; Drug: Velcade plus dexamethasone
Sponsors: Onyx Pharmaceuticals; Onyx Pharmaceuticals
Not yet recruiting - verified April 2012
A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma

Posted: March 28th, 2012, 8:00am MDT

Conditions: Malignant; Pleural; Mesothelioma
Interventions: Biological: TroVax®; Drug: Pemetrexed; Drug: Cisplatin; Dietary Supplement: Vitamin B12; Dietary Supplement: Folic Acid; Drug: Dexamethasone
Sponsors: Wales Cancer Trials Unit; Wales Cancer Trials Unit; Velindre NHS Trust; June Hancock Mesothelioma Research Fund; Velindre Cancer Centre Stepping Stones Appeal
Not yet recruiting - verified March 2012
Treatment of Severe Mucositis Pain With Oral Ketamine Mouthwash

Posted: March 27th, 2012, 8:00am MDT

Condition: Mucositis
Intervention: Drug: Ketamine
Sponsors: West Virginia University; Aaron Cumpston, PharmD
Recruiting - verified March 2012
Dorsal Penile Block for Post-Robotic Prostatectomy Foley Discomfort

Posted: March 26th, 2012, 8:00am MDT

Conditions: Prostate Cancer; Robotic Prostatectomy; Foley Catheter Discomfort
Interventions: Drug: Bupivacaine; Drug: Saline
Sponsors: Columbia University; Columbia University
Recruiting - verified March 2012
$Permalink for 'A Study Of Inotuzumab Ozogamicin Versus Investigator's Choice Of Chemotherapy In Patients With Relapsed Or Refractory Acute Lymphoblastic Leukemia'$
A Study Of Inotuzumab Ozogamicin Versus Investigator's Choice Of Chemotherapy In Patients With Relapsed Or Refractory Acute Lymphoblastic Leukemia

Posted: March 26th, 2012, 8:00am MDT

Condition: Acute Lymphoblastic Leukemia
Interventions: Drug: inotuzumab ozogamicin; Drug: FLAG (fludarabine, cytarabine and G-CSF); Drug: HIDAC (high dose cytarabine); Drug: cytarabine and mitoxantrone
Sponsors: Pfizer; Pfizer; Union Chimique Belge
Not yet recruiting - verified May 2012
Impact of Perioperative Intravenous Fluid Utilization on Postoperative Outcomes

Posted: March 24th, 2012, 8:00am MDT

Conditions: Benign Neoplasm of Intestinal Tract; Primary Malignant Neoplasm of Intestinal Tract; Secondary Malignant Neoplasm of Intestinal Tract
Interventions: Procedure: Normal fluid volume; Procedure: Reduced fluid volume
Sponsors: The Cleveland Clinic; The Cleveland Clinic
Recruiting - verified March 2012
Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

Posted: March 23rd, 2012, 8:00am MDT

Condition: Advanced Solid Tumors, Excluding Breast Cancer
Interventions: Drug: caffeine; Drug: diclofenac; Drug: omeprazole; Drug: midazolam; Drug: TKI258
Sponsors: Novartis; Novartis Pharmaceuticals
Not yet recruiting - verified May 2012
$Permalink for 'Phase II Study of Sipuleucel-T and 1-MT for Patients With Refractory Metastatic Prostate Cancer'$
Phase II Study of Sipuleucel-T and 1-MT for Patients With Refractory Metastatic Prostate Cancer

Posted: March 20th, 2012, 8:00am MDT

Condition: Metastatic Castration Resistant Prostate Cancer
Interventions: Biological: 1-MT; Biological: Sipuleucel-T; Other: Placebo
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Not yet recruiting - verified April 2012
Quality of Life Outcomes Following Minimally Invasive and Open Esophagectomy for Esophageal Cancer

Posted: March 16th, 2012, 8:00am MDT

Condition: Esophageal Cancer
Interventions: Behavioral: Quality of Life instruments, FACT-E, Symptom Assessment Scale, Brief Pain Inventory and Daily Analgesic Log; Behavioral: Quality of Life instruments, FACT-E, Symptom Assessment Scale, Brief Pain Inventory and Daily Analgesic Log
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center
Recruiting - verified May 2012
Anesthesia and Cancer Recurrence im Malignant Melanoma

Posted: March 13th, 2012, 8:00am MDT

Condition: Malignant Melanoma
Interventions: Procedure: Spinal anesthesia with Bupivacaine hyperbar 0.5 %; Procedure: General anesthesia with Sufentanil, Propofol and Rocuronium and Sevoflurane
Sponsors: University Hospital Muenster; University Hospital Muenster
Recruiting - verified March 2012
Nelfinavir and Lenalidomide/Dexamethasone in Patients With Progressive Multiple Myeloma That Have Failed Lenalidomide-containing Therapy

Posted: March 8th, 2012, 8:00am MST

Condition: Multiple Myeloma
Interventions: Drug: Nelfinavir; Drug: Lenalidomide; Drug: Dexamethasone
Sponsors: Swiss Group for Clinical Cancer Research; Swiss Group for Clinical Cancer Research
Recruiting - verified May 2012
Pathway M-1: Sphenopalatine Ganglion Stimulation for the Treatment of Chronic or High Frequency, High Disability Migraine Headache

Posted: February 20th, 2012, 8:00am MST

Conditions: Chronic Migraine; High Frequency, High Disability Migraine
Intervention: Device: ATI Neurostimulation System
Sponsors: Autonomic Technologies, Inc.; Autonomic Technologies, Inc.
Recruiting - verified May 2012
Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant

Posted: February 17th, 2012, 8:00am MST

Conditions: Solid Tumor; Brain Tumor; Lymphoma
Intervention: Other: Blood samples obtained
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified February 2012
Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart Surgery

Posted: February 16th, 2012, 8:00am MST

Conditions: Diseases of Mitral Valve; Aortic Valve Disorder; Atrial Septal Defects; Intracardiac Myxoma
Interventions: Drug: Articaine hydrochloride 2% solution; Drug: Sodium Chloride
Sponsors: Helsinki University Central Hospital; Helsinki University Central Hospital
Recruiting - verified April 2012
Efficacy of Diclofenac BCG Irrigations

Posted: February 14th, 2012, 8:00am MST

Condition: Bladder Cancer
Interventions: Drug: Abitren; Drug: Placebo
Sponsors: Carmel Medical Center; Carmel Medical Center
Not yet recruiting - verified May 2012
Clinical Usefulness and Quality of Life of OROS Hydromorphone in Patients Who Have Not Been Treated With a Strong Opioid

Posted: February 10th, 2012, 8:00am MST

Condition: Pain
Intervention: Drug: Hydromorphone HCI OROS
Sponsors: Janssen Korea, Ltd., Korea; Janssen Korea, Ltd., Korea
Recruiting - verified May 2012
MRI and Diffusion Tensor Imaging of the Motor and Language Pathways to Optimize Brain Tumor Resection

Posted: February 9th, 2012, 8:00am MST

Condition: Brain Cancer
Intervention: Procedure: preoperative fMRI and DTI with tractography
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center
Recruiting - verified May 2012
Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma

Posted: January 25th, 2012, 8:00am MST

Conditions: Cholangiocarcinoma; Liver Neoplasms
Interventions: Drug: floxuridine, dexamethasone; Drug: floxuridine, dexamethasone, gemcitabine hydrochloride; Drug: floxuridine, dexamethasone, gemcitabine hydrochloride, oxaliplatin
Sponsors: Washington University School of Medicine; Washington University School of Medicine
Recruiting - verified May 2012
$Permalink for 'ACE-011 With Lenalidomide+Dexamethasone for Relapsed/Refractory Multiple Myeloma'$
ACE-011 With Lenalidomide+Dexamethasone for Relapsed/Refractory Multiple Myeloma

Posted: January 8th, 2012, 8:00am MST

Condition: Multiple Myeloma
Interventions: Drug: ACE-011; Drug: Lenalidomide; Drug: Dexamethasone
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified May 2012
Palatability of Experimental Cigarettes

Posted: January 3rd, 2012, 8:00am MST

Condition: Smoking
Interventions: Other: Very low level nicotine containing cigarette; Other: Low nicotine level cigarette; Other: Moderate level nicotine cigarette
Sponsors: Masonic Cancer Center, University of Minnesota; Masonic Cancer Center, University of Minnesota
Recruiting - verified May 2012
Community Network Program

Posted: January 3rd, 2012, 8:00am MST

Condition: Psychosocial Problem
Interventions: Behavioral: Health Education; Behavioral: Questionnaires; Behavioral: Telephone Counseling Sessions; Drug: Nicotine Patches
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institutes of Health (NIH)
Recruiting - verified May 2012
Maintenance Plasma Exchange for Neuromyelitis Optica

Posted: December 23rd, 2011, 8:00am MST

Conditions: Neuromyelitis Optica; Neuromyelitis Optica Spectrum Disorder; Recurrent Idiopathic Longitudinally Extensive Transverse Myelitis
Intervention: Procedure: Plasma exchange (PLEX)
Sponsors: Mayo Clinic; Mayo Clinic; CaridianBCT
Not yet recruiting - verified May 2012
Phase I Study of 5-Fluorouracil in Children and Young Adults With Recurrent Ependymoma

Posted: December 21st, 2011, 8:00am MST

Conditions: Central Nervous System Malignancies; Ependymoma
Intervention: Drug: 5-fluorouracil
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified May 2012
Fosaprepitant in Patients Receiving Ifosfamide-based Regimen

Posted: December 8th, 2011, 8:00am MST

Conditions: Sarcoma; Chemotherapy-induced Nausea and Vomiting; Effects of Chemotherapy; Adverse Effects of Medical Drugs
Interventions: Drug: Fosaprepitant; Drug: Dexamethasone; Drug: 5HT3 receptor antagonist; Drug: Ifosfamide-based chemotherapy (AI); Drug: Doxorubicin; Drug: Mesna; Drug: Ifosfamide; Drug: Vincristine
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Merck
Recruiting - verified May 2012
Safety and Efficacy Study of Botulinum Toxin Type A to Treat Glabellar Lines

Posted: December 1st, 2011, 8:00am MST

Condition: Glabellar Frown Lines
Intervention: Biological: MT10109
Sponsors: Medy-Tox; Medy-Tox
Recruiting - verified April 2012
Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma

Posted: November 23rd, 2011, 8:00am MST

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: mibefradil dihydrochloride; Drug: temozolomide; Other: 3'-deoxy-3'-[18F]fluorothymidine; Other: pharmacological study
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI); Tau Therapeutics LLC
Recruiting - verified April 2012
GRN1005 Alone or in Combination With Trastuzumab in Breast Cancer Patients With Brain Metastases

Posted: November 16th, 2011, 8:00am MST

Conditions: Breast Cancer; Brain Metastases
Interventions: Drug: GRN1005; Drug: Trastuzumab
Sponsors: Geron Corporation; Geron Corporation
Recruiting - verified May 2012
Does Serum-DXM Increase Diagnostic Accuracy of the Overnight DXM Suppression Test in the Work-up of Cushing's Syndrome?

Posted: November 15th, 2011, 8:00am MST

Conditions: Cushing's Syndrome; Adrenal Incidentalomas; Alcoholism; Obesity
Intervention:
Sponsors: Haukeland University Hospital; Haukeland University Hospital
Recruiting - verified May 2012
Intravenous Acetaminophen for Craniotomy Patients

Posted: November 9th, 2011, 8:00am MST

Condition: Craniotomy
Interventions: Drug: Acetaminophen; Other: No acetaminophen
Sponsors: Swedish Medical Center; Swedish Medical Center; Cadence Pharmaceuticals
Recruiting - verified May 2012
Defined Green Tea Catechin Extract in Treating Patients With Plasma Cell Neoplasm Or Smoldering Multiple Myeloma

Posted: October 27th, 2011, 8:00am MDT

Conditions: Monoclonal Gammopathy of Undetermined Significance; Smoldering Multiple Myeloma
Interventions: Dietary Supplement: defined green tea catechin extract; Biological: laboratory biomarker analysis
Sponsors: Barbara Ann Karmanos Cancer Institute; Barbara Ann Karmanos Cancer Institute; National Cancer Institute (NCI)
Recruiting - verified April 2012
Silencing Inflammatory Activity by Injecting Nanocort in Patients at Risk for Atherosclerotic Disease

Posted: October 13th, 2011, 8:00am MDT

Conditions: Atherosclerosis; Inflammation
Interventions: Drug: liposomal prednisolone; Drug: Placebo
Sponsors: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Recruiting - verified May 2012
A Study of CDX-1127 in Patients With Select Solid Tumor Types or Hematologic Cancers

Posted: October 12th, 2011, 8:00am MDT

Conditions: CD27 Expressing B-cell Malignancies; CD27 Expressing Solid Tumors; Chronic Lymphocytic Leukemia; Burkett's Lymphoma; Mantle Cell Lymphoma; Primary Lymphoma of the Central Nervous System; Marginal Zone B Cell Lymphoma; Solid Tumor; Metastatic Melanoma; Renal (Clear) Cell Carcinoma; Hormone-refractory Prostate Adenocarcinoma; Ovarian Cancer; Colorectal Adenocarcinoma; Non-small Cell Lung Cancer
Intervention: Drug: CDX-1127
Sponsors: Celldex Therapeutics; Celldex Therapeutics
Recruiting - verified May 2012
Ultra Low Dose Interleukin-2 in Healthy Volunteers

Posted: September 30th, 2011, 8:00am MDT

Condition: Hematologic Diseases
Interventions: Drug: Interleukin-2 (100,000 international units); Drug: Interleukin-2 (200,000 international units)
Sponsors: National Institutes of Health Clinical Center (CC); National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified September 2011
$Permalink for 'Efficacy and Safety of R-HAD Alone or in Combination With Bortezomib in Patients With Relapsed or Refractory MCL'$
Efficacy and Safety of R-HAD Alone or in Combination With Bortezomib in Patients With Relapsed or Refractory MCL

Posted: September 28th, 2011, 8:00am MDT

Condition: Mantle Cell Lymphoma
Interventions: Drug: Rituximab; Drug: High dose Ara-C; Drug: Dexamethasone; Drug: Bortezomib
Sponsors: European Mantle Cell Lymphoma Network; Dr. M. Dreyling (co-chairman); Klinikum der Universitaet Muenchen, Grosshadern; ClinAssess GmbH, Leverkusen; GELARC Service de Pharmacovigilance, Pierre Benite
Recruiting - verified May 2012
Efficacy and Safety of Palonosetron Intravenous in Prevention of Chemotherapy Induced Nausea and Vomiting in Pediatric Patients

Posted: September 21st, 2011, 8:00am MDT

Condition: Chemotherapy-Induced Nausea and Vomiting
Interventions: Drug: Palonosetron; Drug: Palonosetron; Drug: Ondansetron
Sponsors: Helsinn Healthcare SA; Helsinn Healthcare SA
Recruiting - verified May 2012
Pomalidomide in Combination With High Dose Dexamethasone and Oral Cyclophosphamide

Posted: September 9th, 2011, 8:00am MDT

Condition: Myeloma
Interventions: Drug: Pomalidomide; Drug: Dexamethasone; Drug: Cyclophosphamide
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute; Celgene Corporation
Recruiting - verified May 2012
$Permalink for 'A Study to Evaluate the Use of Chloroquine in Combination With VELCADE and Cyclophosphamide in Patients With Relapsed and Refractory Multiple Myeloma'$
A Study to Evaluate the Use of Chloroquine in Combination With VELCADE and Cyclophosphamide in Patients With Relapsed and Refractory Multiple Myeloma

Posted: September 8th, 2011, 8:00am MDT

Condition: Multiple Myeloma
Interventions: Drug: Cyclophosphamide; Drug: Velcade; Drug: Chloroquine
Sponsors: New York University School of Medicine; New York University School of Medicine; Millennium Pharmaceuticals, Inc.
Recruiting - verified April 2012
A Dose Escalation Study of the Histone Deacetylase Inhibitor (HDACi) JNJ 26481585 in Combination With VELCADE (Bortezomib) and Dexamethasone for Patients With Relapsed Multiple Myeloma

Posted: August 30th, 2011, 8:00am MDT

Condition: Multiple Myeloma
Intervention: Drug: JNJ-2641585 / VELCADE / Dexamethasone
Sponsors: Janssen Research & Development, LLC; Janssen Research & Development, LLC
Recruiting - verified May 2012
A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy

Posted: August 18th, 2011, 8:00am MDT

Conditions: Pain; Constipation
Interventions: Drug: oxycodone/naloxone prolonged release (OXN PR) tablets; Drug: oxycodone prolonged release (OxyPR) tablets
Sponsors: Mundipharma Research GmbH & Co KG; Mundipharma Research GmbH & Co KG
Recruiting - verified May 2012
NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma

Posted: August 17th, 2011, 8:00am MDT

Condition: Lymphoblastic Lymphoma
Interventions: Drug: prednisone, vincristine, daunorubicin, PEG-asparaginase, methotrexate, hydrocortisone, cytarabine (IT-MH)A treatment, cyclophosphamide, cytarabine, thioguanine; Drug: PEG- asparaginase, High-Dose Methotrexate (HD-MTX) and Mercaptopurine; Drug: Dexamethasone, Doxorubicin; Vincristine; Mercaptopurine; PEG- Asparaginase, Cyclophosphamide, and Cytarabine; Drug: dexamethasone, cytarabine, etoposide, pegaspargase, clofarabine, cyclophosphamide; Drug: Intrathecal chemotherapy
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital; National University, Singapore
Recruiting - verified April 2012
Bevacizumab With or Without Surgery for Adult Glioblastomas

Posted: August 9th, 2011, 8:00am MDT

Conditions: Glioblastoma; Brain Neoplasm
Intervention: Procedure: Craniotomy
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified April 2012
Beta-Tricalcium Phosphate Bone Graft in Treating Patients Undergoing Surgery For Metastatic Spine Cancer

Posted: July 29th, 2011, 8:00am MDT

Conditions: Adult Spinal Cord Neoplasm; Spinal Bone Metastases; Spinal Cord Compression
Interventions: Procedure: musculoskeletal complications management/prevention; Procedure: bone graft; Procedure: quality-of-life assessment; Other: questionnaire administration
Sponsors: USC/Norris Comprehensive Cancer Center; USC/Norris Comprehensive Cancer Center; National Cancer Institute (NCI)
Recruiting - verified May 2012
Fosaprepitant (EMEND® IV) In Salvage Treatment of Chemotherapy-Induced Vomiting (MK-0517-030 AM1)

Posted: July 28th, 2011, 8:00am MDT

Conditions: Nausea; Vomiting
Interventions: Drug: fosaprepitant dimeglumine; Drug: 5HT3 RA; Drug: dexamethasone
Sponsors: Merck; Merck
Recruiting - verified May 2012
Carfilzomib, Lenalidomide, and Dexamethasone in New Multiple Myeloma Patients

Posted: July 23rd, 2011, 8:00am MDT

Condition: Multiple Myeloma
Interventions: Drug: Carfilzomib; Drug: Lenalidomide; Drug: Dexamethasone
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI); Celgene Corporation; Onyx Therapeutics, Inc.
Recruiting - verified July 2011
Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

Posted: July 21st, 2011, 8:00am MDT

Conditions: Leukemia; Lymphoma
Interventions: Drug: dexamethasone; Drug: methotrexate; Drug: mitoxantrone hydrochloride; Drug: pegaspargase; Drug: temsirolimus; Drug: vincristine sulfate; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2012
Nuvigil or Placebo in Newly Diagnosed Malignant Glioma

Posted: July 21st, 2011, 8:00am MDT

Condition: Malignant Glioma
Interventions: Drug: Nuvigil®; Drug: Placebo
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; H. Lee Moffitt Cancer Center and Research Institute; Cephalon
Recruiting - verified May 2012
Cyclophosphamide and Pulse Dexamethasone With Rapamycin or Hydroxychloroquine

Posted: July 14th, 2011, 8:00am MDT

Condition: Myeloma
Interventions: Drug: Hydroxychloroquine; Drug: Rapamycin
Sponsors: Abramson Cancer Center of the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified May 2012
$Permalink for 'Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma'$
Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma

Posted: July 8th, 2011, 8:00am MDT

Conditions: Brain Cancer; MALIGNANT GLIOMA; Glioblastoma; Anaplastic Astrocytoma (AA); Anaplastic Oligodendroglioma (AO); Anaplastic Oligo-astrocytoma (AOA); Anaplastic Mixed Gliomas; Malignant Glioma NOS
Intervention: Other: Bevacizumab & stereotactic radiotherapy
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Genentech; Columbia University; University of California, San Francisco
Recruiting - verified May 2012
Alloreactive Haploidentical Natural Killer (NK) Cells With Busulfan and Fludarabine/ATG

Posted: July 7th, 2011, 8:00am MDT

Conditions: Leukemia; Chronic Myelogenous Leukemia
Interventions: Drug: Fludarabine; Drug: Busulfan; Procedure: NK cell infusion:; Drug: Interleukin-2; Drug: Anti-Thymocyte Globulin; Procedure: Allogeneic related Stem Cell Transplant; Drug: Tacrolimus; Drug: Methotrexate
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting - verified April 2012
Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma

Posted: July 7th, 2011, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: olaparib; Drug: temozolomide; Genetic: gene expression analysis; Genetic: protein expression analysis; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: diffusion-weighted magnetic resonance imaging; Procedure: dynamic contrast-enhanced magnetic resonance imaging; Procedure: therapeutic conventional surgery
Sponsors: Cancer Research UK; Cancer Research UK
Recruiting - verified April 2012
Bortezomib/Dexamethasone (BD), Followed By Autologous Stem Cell Transplantation and Maintenance Bortezomib/Dexamethasone For the Initial Treatment of Monoclonal Immunoglobulin Deposition Disease (MIDD) Associated With Multiple Myeloma and AL Amyloidosis

Posted: June 27th, 2011, 8:00am MDT

Conditions: Light Chain Deposition Disease (LCDD or MIDD); Light Chain and Heavy Chain Deposition Disease (LHCDD or MIDD); Monoclonal Immunoglobulin Deposition Disease (MIDD); Amyloidosis
Intervention: Drug: Bortezomib/Dexamethasone (BD), Followed By Autologous STC & Maintenance Bortezomib/Dexamethasone
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Millennium Pharmaceuticals, Inc.
Recruiting - verified May 2012

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Rare Cancer News & Clinical Trials » Trial - CNS Tumor

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Trial - CNS Tumor (100 unread)

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