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Trial - Brain Tumor (100 unread)

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Hypernatremia for the Prevention and Treatment of Cerebral Edema in Traumatic Brain Injury

Posted: May 22nd, 2012, 8:00am MDT

Conditions: Traumatic Brain Injury; Subdural Hematoma; Cerebral Contusion; Head Injury; Cerebral Edema
Interventions: Drug: Induced, sustained hypernatremia using hypertonic saline; Drug: Standard of care (hypertonic saline and mannitol; serum sodium)
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Not yet recruiting - verified May 2012
A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression

Posted: May 21st, 2012, 8:00am MDT

Condition: Brain Cancer
Intervention: Other: MRI perfusion and PET/CT scans
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center
Recruiting - verified May 2012
Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma Multiforme

Posted: May 21st, 2012, 8:00am MDT

Condition: Glioblastoma
Intervention: Radiation: Magnetic Resonance Imaging (MRI)
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Recruiting - verified December 2011
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

Posted: May 18th, 2012, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: carboplatin; Drug: etoposide; Drug: ifosfamide; Procedure: therapeutic conventional surgery; Radiation: 3-dimensional conformal radiation therapy; Radiation: intensity-modulated radiation therapy
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Not yet recruiting - verified May 2012
Multi Dose Effects of a Berry Extract Upon Moodand Cognition in Healthy Young Adults

Posted: May 17th, 2012, 8:00am MDT

Condition: Healthy
Intervention: Dietary Supplement: Fresh berry extract.
Sponsors: Northumbria University; Northumbria University; The New Zealand Institute for Plant & Food Research Ltd
Completed - verified May 2012
Implementing a Tool to Identify Risk for Venous Thromboembolism in Cancer Patients

Posted: May 16th, 2012, 8:00am MDT

Conditions: Venous Thromboembolism; Deep-Vein Thrombosis; Pulmonary Embolism; Cancer
Intervention:
Sponsors: Ottawa Hospital Research Institute; Ottawa Hospital Research Institute; The Ottawa Hospital Academic Medical Organization (TOHAMO)
Not yet recruiting - verified May 2012
Social Cognition in Children Treated for a Brain Tumour

Posted: May 11th, 2012, 8:00am MDT

Conditions: Social Behaviour; Brain Neoplasms; Cystic Fibrosis
Intervention:
Sponsors: University Medical Centre Groningen; University Medical Centre Groningen; Radboud University; Universitaire Ziekenhuizen Leuven
Recruiting - verified May 2012
Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients

Posted: May 10th, 2012, 8:00am MDT

Conditions: Seizures (Incl Subtypes); Brain Tumor
Interventions: Drug: Magnesium Sulfate; Other: Sodium Chloride
Sponsors: Fundacion Clinic per a la Recerca Biomédica; Sara Varea
Not yet recruiting - verified May 2012
Type II Diabetes Mellitus in Patients Exposed to Pravastatin and Paroxetine

Posted: May 10th, 2012, 8:00am MDT

Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Pravastatin alone; Drug: Paroxetine alone; Drug: Pravastatin and paroxetine combined
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Active, not recruiting - verified May 2012
Longitudinal Study of Biomarkers

Posted: May 8th, 2012, 8:00am MDT

Condition: Central Nervous System Tumor
Intervention:
Sponsors: Children's Memorial Hospital; Children's Memorial Hospital
Recruiting - verified May 2012
A Prospective Phase III Trial to Compare Stereotactic Radiosurgery Versus Whole Brain Radiation Therapy

Posted: May 3rd, 2012, 8:00am MDT

Condition: Brain Neoplasms
Interventions: Radiation: Stereotactic Radiosurgery (SRS); Radiation: Whole Brain Radiation Therapy (WBRT); Behavioral: Questionnaires; Behavioral: Cognitive Function Tests
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Not yet recruiting - verified May 2012
Lapatinib With Temozolomide and Regional Radiation Therapy for Patients With Newly-Diagnosed Glioblastoma Multiforme

Posted: May 2nd, 2012, 8:00am MDT

Condition: Newly Diagnosed Glioblastoma Multiforme
Intervention: Other: Lapatinib/Temozolomide/radiation
Sponsors: Jonsson Comprehensive Cancer Center; Jonsson Comprehensive Cancer Center; GlaxoSmithKline
Recruiting - verified May 2012
Structural and Functional Imaging and Cognitive Functions in Ovarian Cancer

Posted: April 30th, 2012, 8:00am MDT

Conditions: Fallopian Tube Cancer; Ovarian Cancer; Peritoneal Cancer
Interventions: Other: Neuroimaging & Neuropsychological Evaluation; Other: Neuroimaging & Neuropsychological Evaluation
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Weill Medical College of Cornell University
Recruiting - verified May 2012
A Phase I Study to Investigate Tolerability and Efficacy of ALECSAT Administered to Glioblastoma Multiforme Patients

Posted: April 27th, 2012, 8:00am MDT

Condition: Glioblastoma Multiforme
Intervention: Biological: ALECSAT cell based immunotherapy
Sponsors: CytoVac A/S; CytoVac A/S
Enrolling by invitation - verified April 2012
Cabozantinib in Advanced Solid Malignancies

Posted: April 26th, 2012, 8:00am MDT

Conditions: Lung Cancer; Solid Tumor (Not Breast or Prostate Cancers)
Intervention: Drug: Cabozantinib
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Not yet recruiting - verified May 2012
Human Placental-Derived Stem Cell Transplantation

Posted: April 25th, 2012, 8:00am MDT

Conditions: Mucopolysaccharidosis I; Mucopolysaccharidosis VI; Adrenoleukodystrophy; Niemann-Pick Disease; Metachromatic Leukodystrophy; Wolman Disease; Krabbe's Disease; Gaucher's Disease; Fucosidosis; Batten Disease; Severe Aplastic Anemia; Diamond-Blackfan Anemia; Amegakaryocytic Thrombocytopenia; Myelodysplastic Syndrome; Acute Myelogenous Leukemia; Acute Lymphocytic Leukemia
Intervention: Drug: Human Placental Derived Stem Cell
Sponsors: New York Medical College; New York Medical College
Not yet recruiting - verified April 2012
Studying Gene Expression and Location in Samples From Patients With Brain Tumors

Posted: April 24th, 2012, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Genetic: gene expression analysis; Genetic: genetic linkage analysis; Genetic: microarray analysis; Other: immunohistochemistry staining method; Other: laboratory biomarker analysis
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Active, not recruiting - verified April 2012
A Repeated Instruction by Telephone on the Day Before Colonoscopy to Patients Undergoing Colonoscopy

Posted: April 24th, 2012, 8:00am MDT

Conditions: Bowel Preparation Score; Adenoma
Intervention: Other: telephone education
Sponsors: Fourth Military Medical University; Fourth Military Medical University
Recruiting - verified April 2012
Vorinostat and Concurrent Whole Brain Radiotherapy for Brain Metastasis

Posted: April 23rd, 2012, 8:00am MDT

Condition: Brain Metastasis
Interventions: Drug: Vorinostat; Drug: Placebo
Sponsors: National Taiwan University Hospital; National Taiwan University Hospital
Not yet recruiting - verified April 2012
Safety Study of Replication-competent Adenovirus (Delta-24-rgd) in Patients With Recurrent Glioblastoma

Posted: April 19th, 2012, 8:00am MDT

Conditions: Brain Tumor; Recurring Glioblastoma
Intervention: Biological: delta-24-RGD adenovirus
Sponsors: Erasmus Medical Center; Erasmus Medical Center; VU University Medical Center
Recruiting - verified April 2012
A Study in Recurrent Glioblastoma (GB)

Posted: April 19th, 2012, 8:00am MDT

Condition: Glioblastoma
Interventions: Drug: LY2157299 monohydrate; Drug: Lomustine; Drug: Placebo
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Recruiting - verified May 2012
Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

Posted: April 18th, 2012, 8:00am MDT

Conditions: Brain Neoplasms; Central Nervous System Neoplasms
Interventions: Drug: TPI287; Drug: Bevacizumab
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Archer Biosciences, Inc.
Not yet recruiting - verified April 2012
Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Patients With Brain Tumors

Posted: April 17th, 2012, 8:00am MDT

Conditions: Adult Anaplastic Astrocytoma; Adult Anaplastic Ependymoma; Adult Anaplastic Meningioma; Adult Anaplastic Oligodendroglioma; Adult Brain Stem Glioma; Adult Choroid Plexus Tumor; Adult Craniopharyngioma; Adult Diffuse Astrocytoma; Adult Ependymoblastoma; Adult Ependymoma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Grade I Meningioma; Adult Grade II Meningioma; Adult Medulloblastoma; Adult Meningeal Hemangiopericytoma; Adult Mixed Glioma; Adult Myxopapillary Ependymoma; Adult Oligodendroglioma; Adult Papillary Meningioma; Adult Pilocytic Astrocytoma; Adult Pineal Gland Astrocytoma; Adult Pineoblastoma; Adult Pineocytoma; Adult Subependymal Giant Cell Astrocytoma; Adult Subependymoma; Adult Supratentorial Primitive Neuroectodermal Tumor (PNET); Meningeal Melanocytoma; Nonmalignant Neoplasm; Recurrent Adult Brain Tumor; Tumors Metastatic to Brain
Interventions: Drug: pioglitazone hydrochloride; Other: laboratory biomarker analysis; Radiation: external beam radiation therapy; Radiation: 3-dimensional conformal radiation therapy; Radiation: intensity-modulated radiation therapy; Procedure: management of therapy complications
Sponsors: Comprehensive Cancer Center of Wake Forest University; Comprehensive Cancer Center of Wake Forest University; National Cancer Institute (NCI)
Recruiting - verified April 2012
Prophylactic Cranial Irradiation in Patients With Lung Adenocarcinoma With High Risk of Brain Metastasis

Posted: April 17th, 2012, 8:00am MDT

Condition: Lung Cancer
Intervention: Radiation: Prophylactic Cranial Irradiation
Sponsors: Instituto Nacional de Cancerologia de Mexico; Instituto Nacional de Cancerologia de Mexico
Not yet recruiting - verified May 2012
Chemotherapy-Induced Cognitive Impairment

Posted: April 12th, 2012, 8:00am MDT

Condition: Cognitive Symptoms
Intervention:
Sponsors: Washington University School of Medicine; Jay F. Piccirillo, MD; Washington University Siteman Cancer Center; Barnes-Jewish Hospital Foundation
Recruiting - verified April 2012
An Open-label, Multi-center, Expanded Access Study of Pasireotide s.c. in Patients With Cushing's Disease

Posted: April 12th, 2012, 8:00am MDT

Condition: Cushing's Disease
Intervention: Drug: Pasireotide sub-cutaneous formulation
Sponsors: Novartis; Novartis Pharmaceuticals
Available - verified April 2012
A Pilot Study to Determine the Effect of Sulfasalazine on Glutamate Levels Detected by MRS in Patients With Glioma

Posted: April 11th, 2012, 8:00am MDT

Condition: Brain Tumor
Intervention: Drug: Sulfasalazine
Sponsors: University of Alabama at Birmingham; University of Alabama at Birmingham
Recruiting - verified April 2012
Erlotinib Plus Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases

Posted: April 11th, 2012, 8:00am MDT

Conditions: Lung Adenocarcinoma; Brain Metastases
Interventions: Drug: erlotinib; Drug: pemetrexed; Drug: cisplatin; Drug: erlotinib
Sponsors: Guangzhou Medical College; Guangzhou Medical College
Recruiting - verified April 2012
The Management of Postoperative Craniotomy Pain in Pediatric Patients

Posted: April 10th, 2012, 8:00am MDT

Conditions: Post Craniotomy Surgery; Cancer; Epilepsy; Vascular Malformations; Craniofacial Reconstructive Surgery
Intervention:
Sponsors: Johns Hopkins University; Johns Hopkins University
Enrolling by invitation - verified April 2012
Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme

Posted: April 9th, 2012, 8:00am MDT

Conditions: Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Tumor
Interventions: Drug: aminolevulinic acid; Procedure: therapeutic conventional surgery
Sponsors: Case Comprehensive Cancer Center; Case Comprehensive Cancer Center; National Cancer Institute (NCI)
Not yet recruiting - verified April 2012
Calcium Homeostasis in Acromegaly: Effect of Surgical/Medical Treatment and Comparison With Nonfunctioning Pituitary Tumors

Posted: March 29th, 2012, 8:00am MDT

Conditions: Acromegaly; Nonfunctioning Pituitary Tumor
Intervention:
Sponsors: Emory University; Emory University
Recruiting - verified March 2012
Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas

Posted: March 29th, 2012, 8:00am MDT

Condition: Pediatric High Risk Gliomas
Intervention: Drug: Combination of two marketed drugs (irinotecan and cisplatin)
Sponsors: Hospital Sant Joan de Deu; Hospital Sant Joan de Deu; Fundació Sant Joan de Déu; Spanish National Health System
Recruiting - verified April 2012
Study of DC Vaccination Against Glioblastoma

Posted: March 26th, 2012, 8:00am MDT

Conditions: Glioma; Glioblastoma Multiforme; Neoplasms
Interventions: Procedure: Surgery; Drug: Chemotherapy; Radiation: Radiotherapy; Biological: DC vaccination; Drug: blank placebo
Sponsors: Huashan Hospital; Huashan Hospital; Fudan University
Recruiting - verified March 2012
Impact of Perioperative Intravenous Fluid Utilization on Postoperative Outcomes

Posted: March 24th, 2012, 8:00am MDT

Conditions: Benign Neoplasm of Intestinal Tract; Primary Malignant Neoplasm of Intestinal Tract; Secondary Malignant Neoplasm of Intestinal Tract
Interventions: Procedure: Normal fluid volume; Procedure: Reduced fluid volume
Sponsors: The Cleveland Clinic; The Cleveland Clinic
Recruiting - verified March 2012
Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma

Posted: November 23rd, 2011, 8:00am MST

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: mibefradil dihydrochloride; Drug: temozolomide; Other: 3'-deoxy-3'-[18F]fluorothymidine; Other: pharmacological study
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI); Tau Therapeutics LLC
Recruiting - verified April 2012
$Permalink for 'Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma'$
Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma

Posted: July 8th, 2011, 8:00am MDT

Conditions: Brain Cancer; MALIGNANT GLIOMA; Glioblastoma; Anaplastic Astrocytoma (AA); Anaplastic Oligodendroglioma (AO); Anaplastic Oligo-astrocytoma (AOA); Anaplastic Mixed Gliomas; Malignant Glioma NOS
Intervention: Other: Bevacizumab & stereotactic radiotherapy
Sponsors: Memorial Sloan-Kettering Cancer Center; Memorial Sloan-Kettering Cancer Center; Genentech; Columbia University; University of California, San Francisco
Recruiting - verified May 2012
PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation

Posted: July 8th, 2011, 8:00am MDT

Conditions: Glioblastoma Multiforme; Anaplastic Glioma
Interventions: Drug: PPX (CT2103); Drug: Temozolomide
Sponsors: Brown University; Debora G. Isdale; Yale University; Milton S. Hershey Medical Center; University of Washington; University of Massachusetts, Worcester; Maine Medical Center
Recruiting - verified May 2012
Proton Radiation Therapy for Low Grade Gliomas

Posted: May 17th, 2011, 8:00am MDT

Conditions: Low Grade Gliomas; Protoplasmic Astrocytomas; Fibrillary Astrocytomas; Gemistocytic Astrocytomas; Oligoastrocytomas; Oligodendrogliomas; Other WHO Grade II/IV Gliomas
Intervention: Radiation: Proton radiation
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Cancer Institute (NCI)
Recruiting - verified May 2012
TPI 287 in Breast Cancer Metastatic to the Brain

Posted: April 7th, 2011, 8:00am MDT

Condition: Breast Cancer
Intervention: Drug: TPI 287
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; Archer Biosciences, Inc.
Active, not recruiting - verified April 2012
Bosutinib in Adult Patients With Recurrent Glioblastoma

Posted: March 28th, 2011, 8:00am MDT

Condition: Glioblastoma
Intervention: Drug: bosutinib
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Dana-Farber Cancer Institute; Brigham and Women's Hospital; Pfizer
Recruiting - verified April 2012
A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases

Posted: February 25th, 2011, 8:00am MST

Condition: HER-2 Positive Breast Cancer
Interventions: Drug: Everolimus; Drug: Vinorelbine; Drug: Trastuzumab
Sponsors: UNC Lineberger Comprehensive Cancer Center; UNC Lineberger Comprehensive Cancer Center; Novartis Pharmaceuticals
Recruiting - verified April 2012
Early Cardiac Toxicity of Adjuvant CT in Elderly BC.

Posted: February 18th, 2011, 8:00am MST

Condition: Breast Cancer
Intervention: Drug: epirubicin, cyclophosphamide, docetaxel
Sponsors: Jules Bordet Institute; Jules Bordet Institute; Sanofi-Aventis
Recruiting - verified February 2011
Neurofeedback and Pain

Posted: January 14th, 2011, 8:00am MST

Conditions: Pain; Peripheral Neuropathy
Interventions: Behavioral: EEG biofeedback (BF) Group; Behavioral: Wait-List Control (WLC) Group; Behavioral: Follow UP Questionnaires
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified May 2012
$Permalink for 'GDC-0449 in Treating Younger Patients With Recurrent or Refractory Medulloblastoma'$
GDC-0449 in Treating Younger Patients With Recurrent or Refractory Medulloblastoma

Posted: November 10th, 2010, 8:00am MST

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: vismodegib; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: National Cancer Institute (NCI); Pediatric Brain Tumor Consortium; National Cancer Institute (NCI)
Recruiting - verified April 2012
In-Room PET in Proton Radiation Therapy

Posted: October 25th, 2010, 8:00am MDT

Conditions: Brain Tumor; Head and Neck Tumor; Skull Base Tumor
Intervention: Procedure: PET scan
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Cancer Institute (NCI)
Recruiting - verified May 2012
$Permalink for 'To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer'$
To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Posted: October 15th, 2010, 8:00am MDT

Conditions: Sarcoma; Neuroblastoma; Wilms Tumor; Leukemia; Lymphoma; Brain Tumors
Intervention: Drug: Marqibo
Sponsors: Talon Therapeutics, Inc; Talon Therapeutics, Inc; National Cancer Institute (NCI)
Recruiting - verified May 2012
Prospective Cohort Study With Central Nervous System Evaluation in Diffuse Large B-cell Lymphoma

Posted: September 8th, 2010, 8:00am MDT

Condition: Diffuse Large B-cell Lymphoma
Intervention: Procedure: CSF analysis
Sponsors: Samsung Medical Center; Samsung Medical Center; Asan Medical Center; Yonsei University; National Cancer Center, Korea; Korea Cancer Center Hospital; Korea University
Recruiting - verified May 2012
R04929097 and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Posted: August 25th, 2010, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Biological: bevacizumab; Drug: gamma-secretase/Notch signalling pathway inhibitor RO4929097
Sponsors: National Cancer Institute (NCI); National Cancer Institute (NCI)
Not yet recruiting - verified May 2012
A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis

Posted: July 28th, 2010, 8:00am MDT

Conditions: Estrogen Receptor Negative (ER-Negative) Breast Cancer; Progesterone Receptor Negative (PR-Negative) Breast Cancer; Human Epidermal Growth Factor Receptor 2 Negative (HER2-Negative) Breast Cancer; Brain Metastases
Intervention: Drug: INIPARIB + irinotecan
Sponsors: Sanofi-Aventis; Sanofi-Aventis; UNC Lineberger Comprehensive Cancer Center
Recruiting - verified May 2012
Cellular Immunotherapy Study for Brain Cancer

Posted: June 11th, 2010, 8:00am MDT

Conditions: Gliomas; Anaplastic Astrocytoma; Anaplastic Oligodendroglioma; Anaplastic Mixed Glioma; Glioblastoma Multiforme
Intervention: Drug: alloCTL
Sponsors: University of California, Los Angeles; University of California, Los Angeles; National Institutes of Health (NIH); National Cancer Institute (NCI)
Recruiting - verified June 2010
RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma

Posted: May 11th, 2010, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: gamma-secretase inhibitor RO4929097; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy; Procedure: neoadjuvant therapy; Procedure: therapeutic conventional surgery
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Recruiting - verified May 2012
Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas

Posted: May 7th, 2010, 8:00am MDT

Conditions: Acoustic Schwannoma; Adult Anaplastic Meningioma; Adult Ependymoma; Adult Grade I Meningioma; Adult Grade II Meningioma; Adult Meningeal Hemangiopericytoma; Adult Papillary Meningioma; Neurofibromatosis Type 1; Neurofibromatosis Type 2; Recurrent Adult Brain Tumor
Intervention: Biological: bevacizumab
Sponsors: Northwestern University; Northwestern University
Recruiting - verified May 2012
Prospective Assessment of Quality of Life (QOL) in Pediatric Patients Treated With Radiation Therapy for Brain Tumors and Non-central Nervous System (Non-CNS) Malignancies

Posted: April 30th, 2010, 8:00am MDT

Conditions: Brain Tumors; Non-CNS Malignancies
Intervention: Other: Quality of Life surveys completed at specified timepoints
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; M.D. Anderson Cancer Center
Recruiting - verified April 2012
High Dose Chemotherapy and Stem Cell Transplant for Non-Hodgkin's Lymphoma or Central Nervous System (CNS) Lymphoma

Posted: April 30th, 2010, 8:00am MDT

Conditions: Non-Hodgkin's Lymphoma; CNS Lymphoma
Intervention: Procedure: High-dose chemotherapy with autologous stem cell transplant
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Genentech; Otsuka America Pharmaceutical; Dana-Farber Cancer Institute
Recruiting - verified April 2012
PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma

Posted: April 27th, 2010, 8:00am MDT

Conditions: Glioblastoma; GBM; Glioblastoma Multiforme
Intervention: Drug: PF-00299804
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Dana-Farber Cancer Institute; Brigham and Women's Hospital; Henry Ford Hospital; Pfizer
Recruiting - verified April 2012
Study of the Safety and Efficacy of Dichloroacetate (DCA) in Brain Tumors

Posted: April 23rd, 2010, 8:00am MDT

Condition: Brain Tumor
Intervention: Drug: Dichloroacetate
Sponsors: University of Florida; University of Florida; National Center for Research Resources (NCRR)
Recruiting - verified May 2012
Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Posted: April 19th, 2010, 8:00am MDT

Conditions: Diffuse Intrinsic Pontine Glioma; Brainstem Glioma
Intervention:
Sponsors: Children's Research Institute; Children's Research Institute
Recruiting - verified April 2012
Assessment of Sleep Complaints in Brain Tumor Survivors

Posted: April 12th, 2010, 8:00am MDT

Condition: Brain Tumors
Intervention:
Sponsors: St. Jude Children's Research Hospital; St. Jude Children's Research Hospital
Recruiting - verified April 2012
Brain Metastasis in Breast Cancer Patients

Posted: February 25th, 2010, 8:00am MST

Condition: Breast Cancer
Intervention: Drug: Trastuzumab or Lapatinib
Sponsors: GlaxoSmithKline; GlaxoSmithKline
Active, not recruiting - verified April 2012
$Permalink for 'Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors'$
Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Posted: February 25th, 2010, 8:00am MST

Conditions: Brain and Central Nervous System Tumors; Extra-adrenal Paraganglioma
Interventions: Drug: temozolomide; Drug: vorinostat; Genetic: DNA methylation analysis; Genetic: western blotting; Other: laboratory biomarker analysis; Other: pharmacological study
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Active, not recruiting - verified November 2010
Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)

Posted: February 10th, 2010, 8:00am MST

Conditions: Brain Cancer; Glioblastoma
Interventions: Drug: Standard Dose Bevacizumab; Drug: Low Dose Bevacizumab; Drug: Lomustine
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified May 2012
rRp450-Phase I Trial in Liver Metastases and Primary Liver Tumors

Posted: January 13th, 2010, 8:00am MST

Conditions: Liver Metastases; Primary Liver Cancers
Intervention: Biological: administration of rRp450 into the hepatic artery
Sponsors: Massachusetts General Hospital; Kenneth K. Tanabe, MD; National Cancer Institute (NCI)
Recruiting - verified April 2012
Consent for Obtaining Additional Bone Marrow Specimens at Time of Diagnostic Bone Marrow Procedure

Posted: January 11th, 2010, 8:00am MST

Conditions: Brain Cancer; Cancer
Intervention: Procedure: Bone marrow specimen banking
Sponsors: Stanford University; Stanford University
Recruiting - verified May 2012
Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

Posted: December 2nd, 2009, 8:00am MST

Conditions: Adult Brain Tumor; Adult Brain Stem Glioma; Adult Diffuse Astrocytoma; Adult Ependymoma; Adult Grade II Meningioma; Adult Melanocytic Lesion; Adult Meningeal Hemangiopericytoma; Adult Mixed Glioma; Adult Oligodendroglioma; Adult Pineal Gland Astrocytoma; Adult Pineocytoma; Recurrent Adult Brain Tumor
Interventions: Radiation: proton beam radiation therapy; Procedure: quality-of-life assessment; Other: questionnaire administration
Sponsors: Abramson Cancer Center of the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified May 2012
Magnetic Resonance Imaging in Evaluating Response to RadiationTherapy in Patients With High Grade Glioma

Posted: November 19th, 2009, 8:00am MST

Condition: Brain Tumor
Interventions: Procedure: Magnetic Resonance Imaging; Procedure: Diffusion Tensor Imaging; Procedure: Magnetic Resonance Spectroscopic Imaging; Procedure: Dynamic Contract-Enhanced magnetic resonance imaging; Procedure: Diffusion-weighted magnetic resonance imaging
Sponsors: Abramson Cancer Center of the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified May 2012
Multi-centre UK Study of the Acetylcholinesterase Inhibitor Donepezil in Early Dementia Associated With Parkinson's Disease

Posted: November 16th, 2009, 8:00am MST

Condition: Parkinson's Disease
Intervention: Drug: Donepezil
Sponsors: Newcastle-upon-Tyne Hospitals NHS Trust; Sharon Erb; University of Newcastle Upon-Tyne; University of Cambridge; University of Manchester; University of Birmingham; Bangor University; London School of Economics and Political Science; University College, London; Lancashire Care Trust; Institute for Ageing and Health, Newcastle University; King's College London
Not yet recruiting - verified November 2009
Vascular Endothelial Growth Factor (VEGF) Levels in Brain Tumor Patients

Posted: September 25th, 2009, 8:00am MDT

Conditions: Glioma; Meningioma
Intervention: Procedure: Blood test
Sponsors: Marquette General Health System; Marquette General Health System; Upper Michigan Brain Tumor Center
Withdrawn - verified April 2012
GDC-0449 in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery

Posted: September 18th, 2009, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: Hedgehog antagonist GDC-0449; Procedure: therapeutic conventional surgery
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Active, not recruiting - verified May 2012
Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma

Posted: September 17th, 2009, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: cediranib maleate; Drug: cilengitide; Other: enzyme-linked immunosorbent assay; Other: flow cytometry; Other: laboratory biomarker analysis; Procedure: magnetic resonance imaging
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Recruiting - verified May 2012
Expanded Access Trial of Plant Expressed Recombinant Glucocerebrosidase (prGCD) in Patients With Gaucher Disease

Posted: August 18th, 2009, 8:00am MDT

Condition: Gaucher Disease
Intervention: Drug: Plant cell expressed recombinant glucocerebrosidase (prGCD)
Sponsors: Protalix; Protalix
Available - verified May 2012
A Pilot Study of Using Video Images in Advance Care Planning in Malignant Glioma Patients

Posted: August 7th, 2009, 8:00am MDT

Condition: Advanced Brain Cancer
Intervention: Behavioral: Video intervention
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Foundation for Informed Medical Decision Making
Completed - verified April 2012
Protocol to Distinguish Tumor Recurrence From Treatment-Related Necrosis in Patients With High Grade Gliomas

Posted: July 20th, 2009, 8:00am MDT

Condition: Recurrent High Grade Gliomas
Intervention: Device: 3T MRI
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center
Recruiting - verified May 2012
Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment

Posted: June 27th, 2009, 8:00am MDT

Conditions: Brain and Central Nervous System Tumors; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: pazopanib hydrochloride; Other: pharmacological study
Sponsors: National Cancer Institute (NCI); Children's Oncology Group; National Cancer Institute (NCI)
Active, not recruiting - verified August 2011
Treatment of Recurrent Primary or Secondary Central Nervous System (CNS) Lymphoma With ALIMTA (Pemetrexed)

Posted: June 5th, 2009, 8:00am MDT

Condition: Central Nervous System Lymphoma
Intervention: Drug: pemetrexed
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Eli Lilly and Company; Dana-Farber Cancer Institute
Recruiting - verified April 2012
Evaluation of [18F]-FMISO for Non Operated Glioblastoma

Posted: May 19th, 2009, 8:00am MDT

Condition: Glioblastoma
Intervention: Procedure: 18F]-FMISO PET-CT
Sponsors: University Hospital, Bordeaux; University Hospital, Bordeaux
Recruiting - verified April 2012
Ramucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma Multiforme

Posted: May 7th, 2009, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Biological: anti-PDGFR alpha monoclonal antibody IMC-3G3; Biological: ramucirumab
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI); ImClone LLC
Recruiting - verified April 2012
MsFLASH-01: Escitalopram for Menopausal Symptoms in Midlife Women

Posted: May 5th, 2009, 8:00am MDT

Conditions: Hot Flashes; Menopause; Vasomotor Symptoms
Interventions: Drug: Escitalopram; Other: Placebo
Sponsors: Fred Hutchinson Cancer Research Center; Fred Hutchinson Cancer Research Center; National Institute on Aging (NIA); Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); National Center for Complementary and Alternative Medicine (NCCAM); Office of Research on Women's Health (ORWH)
Completed - verified May 2012
Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients

Posted: April 3rd, 2009, 8:00am MDT

Condition: Brain Cancer
Intervention: Behavioral: Questionnaire
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified April 2012
Monthly SOM230C for Recurrent or Progressive Meningioma

Posted: March 9th, 2009, 8:00am MDT

Condition: Meningioma
Intervention: Drug: SOM230C
Sponsors: Dana-Farber Cancer Institute; Patrick Y. Wen, MD; Brigham and Women's Hospital; Massachusetts General Hospital; Novartis
Active, not recruiting - verified April 2012
Randomized Gefitinib Trial

Posted: December 10th, 2008, 8:00am MST

Condition: Non Small Cell Lung Cancer
Interventions: Drug: Gefitinib; Drug: Platinum
Sponsors: Fondazione Humanitas per la Ricerca; Fondazione Humanitas per la Ricerca
Completed - verified October 2010
Autologous Dendritic Cells Pulsed With Autologous Apoptotic Tumor Cells Administered to Patients With Brain Tumors

Posted: December 5th, 2008, 8:00am MST

Condition: Brain Tumors
Interventions: Drug: DC/AAT; Drug: DC/AAT-Flu; Drug: DC/KLH
Sponsors: Rockefeller University; Rockefeller University; Memorial Sloan-Kettering Cancer Center
Recruiting - verified May 2012
Chemotherapeutic Agents in Brain/Breast

Posted: November 20th, 2008, 8:00am MST

Conditions: Breast Cancer; Metastatic Cancer
Interventions: Drug: capecitabine; Drug: cyclophosphamide; Drug: doxorubicin hydrochloride; Drug: gemcitabine hydrochloride; Drug: lapatinib ditosylate; Drug: paclitaxel; Drug: vinorelbine ditartrate; Drug: Trastuzumab
Sponsors: Case Comprehensive Cancer Center; Case Comprehensive Cancer Center; Department of Defense; National Cancer Institute (NCI)
Recruiting - verified May 2012
ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Posted: October 9th, 2008, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: temozolomide; Drug: veliparib; Genetic: DNA methylation analysis; Genetic: gene expression analysis; Genetic: mutation analysis; Genetic: proteomic profiling; Other: high performance liquid chromatography; Other: immunoenzyme technique; Other: laboratory biomarker analysis; Other: mass spectrometry; Other: pharmacogenomic studies; Other: pharmacological study; Procedure: adjuvant therapy; Radiation: radiation therapy
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Completed - verified May 2012
Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the Urothelium

Posted: September 18th, 2008, 8:00am MDT

Condition: Bladder Cancer
Interventions: Radiation: PCI; Other: Brain X-ray
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified May 2012
Brain Tumor Patient-Caregiver Congruence, MD Anderson Symptom Inventory-Brain Tumor Module (MDASI-BT)

Posted: September 5th, 2008, 8:00am MDT

Condition: Brain Tumor
Intervention: Behavioral: Questionnaire
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Active, not recruiting - verified May 2012
Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL

Posted: August 13th, 2008, 8:00am MDT

Conditions: Brain and Central Nervous System Tumors; Lymphoma; Neurotoxicity
Interventions: Biological: Rituximab; Drug: Cytarabine; Drug: Methotrexate; Drug: Motexafin gadolinium; Drug: Procarbazine hydrochloride; Drug: Vincristine sulfate; Radiation: Radiation therapy
Sponsors: Northwestern University; Northwestern University; Pharmacyclics
Withdrawn - verified May 2012
Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)

Posted: July 25th, 2008, 8:00am MDT

Conditions: Glioblastoma; Glioma; Astrocytoma
Interventions: Drug: Temozolomide; Radiation: Radiotherapy
Sponsors: Schering-Plough; Schering-Plough
Completed - verified May 2012
Magnetic Resonance Temperature Imaging & Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors

Posted: July 21st, 2008, 8:00am MDT

Condition: Brain Tumor
Intervention: Procedure: Visualase® Thermal Therapy System
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; BioTex, Inc.
Recruiting - verified May 2012
A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases

Posted: March 28th, 2008, 8:00am MDT

Conditions: Nervous System Neoplasms; Brain Diseases; Central Nervous System Diseases; Neoplasm Metastasis; Brain Neoplasms
Interventions: Drug: ABT-888; Radiation: Whole Brain Radiation Therapy
Sponsors: Abbott; Abbott
Recruiting - verified May 2012
Assessment of 18FLT PET-CT for Volume Definition of High-grade Gliomas (GLIO-TEP)

Posted: February 15th, 2008, 8:00am MST

Conditions: High-grade Glioma; Astrocytoma; Glioblastoma
Intervention: Radiation: 18F Fluorothymidine PET CT
Sponsors: University Hospital, Bordeaux; University Hospital, Bordeaux
Completed - verified May 2012
Dasatinib in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma

Posted: January 30th, 2008, 8:00am MST

Conditions: Brain and Central Nervous System Tumors; Liver Cancer; Lymphoma; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: dasatinib; Other: pharmacological study
Sponsors: National Cancer Institute (NCI); Southwest Oncology Group; National Cancer Institute (NCI)
Recruiting - verified May 2012
Ph I Dasatinib + Erlotinib in Recurrent MG

Posted: January 25th, 2008, 8:00am MST

Conditions: Glioblastoma; Gliosarcoma
Intervention: Drug: Erlotinib and Dasatinib
Sponsors: Duke University; Duke University; Bristol-Myers Squibb; Genentech
Completed - verified April 2012
A Phase I Study of ABT 510 for Newly Diagnosed Glioblastoma Multiforme

Posted: December 26th, 2007, 8:00am MST

Condition: Brain Tumor
Intervention: Drug: ABT 510
Sponsors: University of Alabama at Birmingham; University of Alabama at Birmingham
Completed - verified May 2012
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Karenitecin in Pediatric Patients With Refractory or Recurrent Solid Tumors N10010)

Posted: December 20th, 2007, 8:00am MST

Condition: Solid Tumors
Intervention: Drug: Kareniticin and cyclophosphamide
Sponsors: Baylor College of Medicine; Baylor College of Medicine; Pediatric Brain Tumor Consortium
Completed - verified May 2012
Gossypol in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Posted: October 5th, 2007, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: R-(-)-gossypol acetic acid; Genetic: protein expression analysis; Other: immunoenzyme technique; Other: laboratory biomarker analysis
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Active, not recruiting - verified April 2012
Early Detection of Cardiotoxicity During Sunitinib or Sorafenib Chemotherapy Using Cardiac Biomarkers

Posted: September 18th, 2007, 8:00am MDT

Condition: Advanced Cancers
Intervention: Behavioral: Questionnaire
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center
Recruiting - verified May 2012
Hydroxychloroquine, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Posted: June 13th, 2007, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: hydroxychloroquine; Drug: temozolomide; Genetic: mutation analysis; Genetic: polymerase chain reaction; Other: immunologic technique; Other: laboratory biomarker analysis; Other: pharmacological study; Procedure: adjuvant therapy; Radiation: 3-dimensional conformal radiation therapy; Radiation: intensity-modulated radiation therapy
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Active, not recruiting - verified May 2012
Pazopanib in Treating Patients With Recurrent Glioblastoma

Posted: April 9th, 2007, 8:00am MDT

Condition: Brain and Central Nervous System Tumors
Intervention: Drug: pazopanib hydrochloride
Sponsors: National Cancer Institute (NCI); North American Brain Tumor Consortium; National Cancer Institute (NCI)
Completed - verified October 2008
Erlotinib and Sorafenib in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Posted: March 7th, 2007, 8:00am MST

Condition: Brain and Central Nervous System Tumors
Interventions: Drug: erlotinib hydrochloride; Drug: sorafenib tosylate; Genetic: gene expression analysis; Genetic: mutation analysis; Other: immunohistochemistry staining method; Other: laboratory biomarker analysis; Other: mass spectrometry; Other: pharmacological study; Procedure: biopsy
Sponsors: Sidney Kimmel Comprehensive Cancer Center; Sidney Kimmel Comprehensive Cancer Center; National Cancer Institute (NCI)
Completed - verified May 2012
Levetiracetam in Treating Patients With Seizures Caused by Brain Metastases

Posted: December 20th, 2006, 8:00am MST

Conditions: Brain and Central Nervous System Tumors; Seizure; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: levetiracetam; Procedure: quality-of-life assessment
Sponsors: Northwestern University; Northwestern University; National Cancer Institute (NCI)
Withdrawn - verified May 2012

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Rare Cancer News & Clinical Trials » Trial - Brain Tumor

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Trial - Brain Tumor (100 unread)

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